To disable Auto Run:

) Go to Start-> Run ( Win +R ) , type gpedit.msc and press ENTER








2) You will get Group policy object editor

For Widows Vista:browse to Windows Components \ AutoPlay Policies, and change the value of "Turn off Autoplay" to enabled.





For Windows XP:select Administrative Templates \ System in the tree view.





Double click "Turn off Autoplay" in right pane and set the radio button to Enabled,and change the "Turn off Autoplay on" to All Drives.